SciSimulator

Estimating Molecular Size: Oil Film Method

Estimating Molecular Size Using the Oil Film Method

Drop oleic acid onto a water surface to form a monomolecular film, then estimate the molecular diameter by measuring the film area

Graph paper (2 cm × 2 cm grid)Lycopodium powder dusted on water surface

Experiment Controls

Oleic Acid–Alcohol Solution Concentration1:10000
1:1000001:1000
Volume per Drop0.05 mL
0.01 mL0.10 mL

Procedure

  • ① Prepare the oleic acid–alcohol solution (known concentration)
  • ② Measure a fixed volume of solution with a graduated cylinder
  • ③ Lightly dust the water surface with a thin, even layer of lycopodium powder
  • ④ Drop one drop of the solution onto the water surface
  • ⑤ Trace the outline of the oil film after it stabilizes
  • ⑥ Calculate the film area using graph paper

Principle

d = V / S

Assuming oleic acid molecules are spherical and form a close-packed monomolecular layer on the water surface, the thickness of the oil film equals the diameter d of one molecule. Given the volume V of pure oleic acid and the film area S, the molecular diameter is d = V / S. The molecular diameter measured by this method is typically on the order of 10⁻¹⁰ m.

Experimental Tips

• Spread the lycopodium powder evenly—do not apply too thick a layer

• Add the drop gently to avoid splashing the water

• Wait until the oil film has fully spread and stabilized before tracing the outline

• Count partial grid squares as one-half